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  Isha Jain, PhD (CV)    Principal Investigator (

Isha received her undergraduate degree in Chemical and Physical Biology from Harvard University. There, she worked in the lab of Erin O’Shea on bacterial chromosome segregation. Subsequently, she joined the Harvard-MIT Program in Health Sciences and Technology. During her PhD, she worked in the labs of Vamsi Mootha and Warren Zapol, where she made the discovery that hypoxia could serve as a therapy for mitochondrial disorders. This work has led to a Phase 1 clinical trial. Isha began as a UCSF Sandler Faculty Fellow in Summer 2018 and will be starting as an Assistant Professor at the Gladstone Institutes and UCSF in 2020/2021.


     Giselle Avina, B.S.      Admin. Assistant

Giselle was born and raised in the SF Bay Area and received her BS in personality psychology from Saint Mary’s College of California. There, she worked under Dr. Paul Zarnoth, doing research on the relationship between cognitive styles and interpersonal influence in group decision making. Now, as an administrative assistant, she is inspired by all of the incredible contributions being made in science today. In her free time, she loves to spend time at the beach, meditate, hike, read, and play video games.

    Kirsten Chen, B.S.    BMS PhD Student

Kirsten grew up in China and earned her BS from University of North Carolina, Chapel Hill. There she completed a double major in chemistry and biology. At UNC, she worked in the lab of Dr. Steve Hursting on metabolic reprogramming during cancer progression to metastasis and differential responses to folate deficiency in a murine model of triple-negative breast cancer. As a BMS student, Kirsten hopes to use experimental and computational approaches to study the complexities of biological systems and disease. Outside of work, she enjoys dancing, traveling and exploring good food and coffee.


   Alan Baik, M.D.      Cardiology Fellow

Alan was born in Los Angeles and attended Harvard University, where he majored in biology. He completed medical school and internal medicine residency at UCSF. As a Sarnoff Cardiovascular Research Fellow, he worked in the lab of Bill Kaelin at the Dana-Farber Cancer Institute, studying the mechanisms of remote ischemic preconditioning in a murine model of cardiac ischemia-reperfusion. Alan is currently a cardiology fellow at UCSF, interested in better understanding oxygen metabolism and signaling in myocardial infarction and cardiovascular disease.


Ankur Garg, PhD Postdoctoral Fellow

Ankur attended IIT Delhi for her undergraduate studies in Biochemical Engineering and Biotechnology. She received her PhD in Molecular Biology and Genetics, in the lab of Xin Zhang at Columbia University studying the role of Fgf signaling in tear gland development. During a post-doc at UCSD, she worked in the lab of Xin Sun where she studied pulmonary neuroendocrine cells. She is now interested in studying the signaling mechanisms underlying hypoxia as a therapeutic intervention for neurodegenerative and metabolic disorders.


   Alec Barrios, B.S.    Research Specialist

Alec was born in Whittier and earned his BS from the University of California, Santa Barbara, where he majored in pharmacology. At UCSB, he worked in the lab of Dr. Joel Rothman on the mechanism of cellular reprogramming in pharyngeal tissue and the effects of reprogramming on mitochondrial function. As a research associate, Alec is studying the role of acute vs. chronic hypoxia on whole-body adaptations, with the goal of developing novel therapies for states of ischemia.


  Bruno Queliconi, PhD   Postdoctoral Fellow

Bruno was born and raised in Sao Paulo, Brazil, where he obtained a Bachelor’s in Biology and a Ph.D. in Biochemistry and Molecular Biology, both from the University of Sao Paulo. During his PhD studies, he focused on mitochondrial physiology and ischemic damage working with Prof. Alicia Kowaltwoski.  During his postdoc, he initially worked under Dr. Noriyuki Matsuda and Dr. Keiji Tanaka to study protein-protein interactions in Parkinson’s disease followed by working with Prof. Daria Mochly-Rosen at Stanford University on peptides as drug candidates for cardiac diseases.


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    Galih Haribowo, PhD     Postdoctoral Fellow

Galih received his bachelor’s degree in Biology from Gadjah Mada University. He then joined the labs of Joost Holthuis at Utrecht University and Anne-Claude Gavin at the EMBL-Heidelberg to study protein-lipid interactions for his master’s degree. During his PhD, he worked in the labs of Howard Riezman at University of Geneva and Maya Schuldiner at the Weizmann Institute of Science, studying the roles of sphingolipid in neurodegenerative disease and ischemia-reperfusion injury. Galih is currently interested in understanding nutrient dependencies of cells under hypoxia and ischemia.


   Brandon Desousa B.S.     BMS PhD Student

Brandon was born and raised in South Florida. He received a B.S. in Biochemistry and Neuroscience at the University of Miami. There, he worked on how neural stem cells can contribute to recovery after a brain injury. He then joined Dr. Ajit Divakaruni’s mitochondrial bioenergetics lab at UCLA and studied the bioenergetics of glioblastoma and macrophage inflammatory activation. Outside of the lab, Brandon enjoys discovering new films at independent cinemas, and working towards crafting the perfect cup of coffee.


      Saahil Chadha        Undergrad Student

Saahil grew up in Minneontka, Minnesota and is an undergraduate at UC Berkeley studying Computer Science and Molecular & Cell Biology. He previously worked with researchers at the University of Minnesota to study the paleogenomics of proteins involved in circadian rhythm functionality in cyanobacteria. At the Jain Lab, Saahil is analyzing high-throughput datasets for several projects related to vitamins and oxygen. In his free time, Saahil likes reading biographies, playing board games, and (like most of the lab) drinking some great coffee!